I moved your thread to VX you will get more hits here.
For games it isn't really pony centered but a great time killer is Stardew Valley it's like harvest moon on steroids.
MLP Fighting is Magic
2D fighting game, was canceled by the studio over copyright infringement but someone leaked it. You can find different versions of it now where people fixed it up or added characters and such. Takes a bit of looking but it's worth the effort. Great game.
Esoteric comics? Do you have an example?
Pony Platforming Project III: Minty Fresh Adventure is a fantastic Flash platformer.
For a longer game, Super Lesbian Horse RPG is an awesomely cute pony RPG from Bobby Schroeder. Lawyers forced him to change it into a generic Super Lesbian Animal RPG, but the original pony version is still available online: https://gamejolt.com/games/super-lesbian-horse-rpg/110689/download/build/273337
Equestriabound is a flawless total conversion of Earthbound to MLP. Every character from the show fits the new story perfectly, making this the second greatest pony RPG of all time. Requires an SNES emulator, but the rom itself can be found here: http://www.romhacking.net/hacks/1973/
Stardew Valley is fun the first time around, but every time I've tried setting up a new farm I run out of steam after the first winter since I already minmaxed my win to completion on everything else.
Oh man, not enough people talk about this. The remixed chiptunes are great, I've played it multiple times, really comfy to play if you have a cfw 3ds.
I still really like Ponymon.
Sometimes I think about making a Pokémon plus Ponymon game, but I have no idea how Ponymon types would interact with Pokémon types.